منابع مشابه
The natural history of type 1A diabetes.
We can now predict the development of Type 1A (Immune Mediated) diabetes primarily through the determination of four biochemically characterized islet autoantibodies [insulin, GAD65, IA-2 (ICA512) and (Znt8)]. Prediction is possible because beta-cell destruction is chronically progressive and very slow in most, but not all individuals. We can also prevent type 1A diabetes in animal models and a...
متن کامل[Natural history of type 1 diabetes].
The natural history of autoimmune type 1 diabetes in children is associated with the appearance of islet autoantibodies early in life, which is influenced by genetic and environmental factors. Once islet autoantibodies have developed, the progression to diabetes in antibody-positive individuals is determined by the age of antibody appearance and by the magnitude of the autoimmunity, in turn rel...
متن کاملNatural History of Type 1 Diabetes
The natural history of autoimmune type 1 diabetes in children is associated with the appearance of islet autoantibodies early in life, which is influenced by genetic and environmental factors. Once islet autoantibodies have developed, the progression to diabetes in antibody-positive individuals is determined by the age of antibody appearance and by the magnitude of the autoimmunity, in turn rel...
متن کاملDifferentiation of Diabetes by Pathophysiology, Natural History, and Prognosis
The American Diabetes Association, JDRF, the European Association for the Study of Diabetes, and the American Association of Clinical Endocrinologists convened a research symposium, "The Differentiation of Diabetes by Pathophysiology, Natural History and Prognosis" on 10-12 October 2015. International experts in genetics, immunology, metabolism, endocrinology, and systems biology discussed gene...
متن کاملNatural history and immunopathogenesis of type 1 diabetes.
Type 1 diabetes (T1D) develops in the majority of cases as result of chronic progressive β-cell destruction. This inflammatory damage depends on a selective loss of immune tolerance, that leads to an extensive infiltration of both helper and cytotoxic T-lymphocytes in the pancreatic islets. The autoimmune mechanism is proven by the presence of a pool of autoantibodies (Abs) against structural a...
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ژورنال
عنوان ژورنال: Psychology & Psychological Research International Journal
سال: 2017
ISSN: 2576-0319
DOI: 10.23880/pprij-16000139